2008

Trinkle-Mulcahy L., Boulon S., Lam Y.W., Urcia R., Boisvert F.M., Vandermoere F., Morrice N.A., Swift S., Rothbauer U., Leonhardt H. and Lamond A.I. Identifying specific protein interaction partners using quantitative mass spectrometry and bead proteomes. J Cell Biol. 183:223-39, 2008.

Moorhead GB, Trinkle-Mulcahy L, Nimick M, De Wever V, Campbell DG, Gourlay R, Lam YW, Lamond AI. Moorhead GB, Trinkle-Mulcahy L, Nimick M, De Wever V, Campbell DG, Gourlay R, Lam YW, Lamond AI. BMC Biochem. 9:28, 2008.

Trinkle-Mulcahy, L. and Lamond, A.I. Nuclear functions in space and time: Gene expression in a dynamic, constrained environment. FEBS Lett. 582:1960-70, 2008.

2007

Trinkle-Mulcahy, L. and Lamond, A.I. Toward a high-resolution view of nuclear dynamics. Science. 318:1402-07, 2007.

Trinkle-Mulcahy, L. and Swift, S. Caught on camera with another protein - Just good friends or something more? A Guide to Localization, Colocalization and Interaction on the Light Microscope. In Focus (Proceedings of the Royal Microscopy Society), 8:4-15, 2007.

Moorhead, G.B.G., Trinkle-Mulcahy, L. and Ulke-Lemee, A. Emerging roles of nuclear protein phosphatases. Nat. Rev. Mol. Cell Biol. 3:234-44, 2007.

Ulke-Lemée A, Trinkle-Mulcahy L, Chaulk S, Bernstein NK, Morrice N, Glover M, Lamond AI and Moorhead GB. The nuclear PP1 interacting protein ZAP3 (ZAP) is a putative nucleoside kinase that complexes with SAM68, CIA, NF110/45, and HNRNP-G. Biochim Biophys Acta. 10:1339-50, 2007.

2006

Trinkle-Mulcahy, L., Andersen, J., Lam, Y.W., Moorhead, G., Mann, M. and Lamond, A.I. Repo-Man recruits PP1γ to chromatin and is essential for cell viability. J. Cell Biol. 172:679-92, 2006.

Vagnarelli, P., Hudson, D.F., Ribeiro, S.A., Trinkle-Mulcahy, L., Spence, J.M., Lai, F., Farr, C.J., Lamond, A.I. and Earnshaw, W.C.. Condensin and Repo-Man/PP1 co-operate in the regulation of chromosome architecture during mitosis. Nat. Cell Biol. 8:1133-42, 2006.

Trinkle-Mulcahy, L.
and Lamond, A.I. Mitotic phosphatases: no longer silent partners. Current Opinion in Cell Biology. 18:623-31, 2006.

Leung, A.K., Trinkle-Mulcahy, L., Lam, Y.W., Andersen, J.S., Mann, M. and Lamond, A.I. NoPdb: Nucleolar Proteome Database. Nucleic Acids Res. 34:D218-20, 2006.

Trinkle-Mulcahy, L., Chusainow, J., Lam, Y.W., Swift, S. and Lamond, A.I. Visualization of intracellular PP1 targeting through transiently and stably expressed fluorescent protein fusions. Methods in Molecular Biology. Vol.. 365:133-54; Protein Phosphatase Protocols, Ed. G. Moorhead, Humana Press, 2006.


2005

Lam, Y.W., Trinkle-Mulcahy, L. and Lamond, A.I. The Nucleolus. J. Cell Sci., 118:1335-1337, 2005.


Swift, S.R., Thomson, C., Appleton, P., Lam, Y.W. and L. Trinkle-Mulcahy. Basic principles deconvolution microscopy. Proc. Royal Mic. Soc., 40, 2005.

Chusainow, J.C., Ajuh, P.M., Trinkle-Mulcahy, L., Sleeman, J.E., Ellenberg, J. and Angus I. Lamond. "FRET analyses of the U2AF complex localize the U2AF35/U2AF65 interaction in vivo and reveal a novel self-interaction of U2AF35" RNA, 11:1201-14, 2005

2004

Swift, S.R. and L. Trinkle-Mulcahy. Basic principles of FRAP, FLIM and FRET. Proc. Royal Mic. Soc., 39:3-10, 2004.

2003

Trinkle-Mulcahy, L., Andrews, P.D., Wickramasinghe, S., Sleeman, J., Prescott, A., Lam, Y.W., Lyon, C., Swedlow, J.R. and Lamond, A.I. Time-lapse imaging reveals dynamic relocalization of PP1γ throughout the mammalian cell cycle. Mol. Biol. Cell, 14:107-117, 2003.

Sleeman, J.E., Trinkle-Mulcahy, L., Prescott, A., Ogg, S.C. and Angus I. Lamond. "Cajal body proteins SMN and Coilin show differential dynamic behaviour in vivo" J. Cell Sci., 116:2039-2050, 2003.

2002

Kimber, W.A., Trinkle-Mulcahy, L., Cheung, P.C.F., Deak, M., Marsden, L.J., Kieloch, A., Watt, S., Javiers, R.T., Gray, A., Downes, C.P., Lucocq, J.M. and Alessi, D.R. "Evidence that the tandem-pleckstrin-homology-domain-containing-protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo." Biochem. J., 361:525-536, 2002.

2001

Trinkle-Mulcahy, L., Sleeman, J.E. and Lamond, A.I. Dynamic targeting of protein phosphatase 1 within the nuclei of living mammalian cells. J. Cell Science. 114:4219-4228, 2001.

Miller, G., Panov, K.I., Friedrich, J.K., Trinkle-Mulcahy, L., Lamond, A.I. and Zomerdijk, J.C.B.M. hRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promoters. EMBO J. 20:1373-1382, 2001.

Cheung, P.C.F., Trinkle-Mulcahy, L., Cohen, P. and Lucocq, J. M. Characterisation of a novel phosphatidylinositol 3-phosphate-binding protein containing two FYVE fingers in tandem that is targeted to the Golgi. Biochem. J. 355:113-121, 2001.

2000

1999

Trinkle-Mulcahy, L., Ajuh, P., Prescott, A., Cohen, S., Claverie-Martin, F., Lamond, A.I. and Cohen, P. Nuclear organisation of NIPP-1, a nuclear subunit of protein phosphatase 1 that associates with pre-mRNA splicing factors. J. Cell Science. 112:157-168, 1999.

Chang, A.C.YU., Sohlberg, B., Trinkle-Mulcahy, L., Claverie-Martin, F., Cohen, P. and Cohen, S.N. Alternative splicing regulates the production of ARD-1 endoribonuclease and NIPP-1, an inhibitor of protein phosphatase-1, as isoforms encoded by the same gene. Gene. 240:45-55, 1999.

1998

1997

Kreivi, J.-P., Trinkle-Mulcahy, L., Lyon, C.E., Morrice, N.A., Cohen, P. and Lamond, A.I. Purification and characterisation of p99, a nuclear modulator of protein phosphatase 1 activity. FEBS Lett. 420:57-62, 1997.

Siegman, M.J., Mooers, S.U., Li, C., Narayan, S., Trinkle-Mulcahy, L., Hartshorne, D.J., and Butler, T.M. Phosphorylation of a high molecular weight (~600 kDa) protein regulates catch in invertebrate smooth muscle. J. Mus. Res. Cell Motility. 18: 655-670, 1997.

Siegman, M.J., Butler, T.M. Mooers, S.U., Trinkle-Mulcahy, L., Narayan, S., Stirewalt, W., and Starcher, B. Hypertrophy of colonic smooth muscle: structural remodeling, chemical composition and force output. Am. J. Physiol. 272: G1560-G1570, 1997.

Siegman, M.J., Butler, T.M., Mooers, S.U., Trinkle-Mulcahy, L., Narayan, S., Adam, L., Chacko, S., Haase, H., and Morano, I. Hypertrophy of colonic smooth muscle: contractile proteins, shortening velocity and regulation. Am. J. Physiol. 272:G1571-G1580, 1997.

1996

1995

Trinkle-Mulcahy, L., Ichikawa, K., Hartshorne, D.J., Siegman, M.J., and Butler T.M. Thiophosphorylation of the 130 kDa subunit is associated with a decreased activity of myosin light chain phosphatase in alpha-toxin-permeabilized smooth muscle. J. Biol. Chem. 270:18191-18194, 1995.

1994

Trinkle-Mulcahy, L., M.J. Siegman and T.M. Butler. Metabolic characteristics of alpha-toxin permeabilized smooth muscle. Am. J. Physiol. 266:C1673-C1683, 1994.

1993

1992

Trinkle, L.A., D. Beasley and R.S. Moreland. Interleukin-1beta alters actin expression and inhibits contraction of rat thoracic aorta. Am. J. Physiol. 262:C828-C833, 1992.











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